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There are five types of insulin. They vary by onset (how soon they start to work), peak (how long they take to kick into full effect) and duration (how long they stay in your body).
You may have to take more than one type of insulin, and these needs may change over time (and can vary depending on your type of diabetes).
1.Rapid-acting insulin
Examples: Humalog (lispro), NovoLog (aspart), Apidra (glulisine)
Rapid-acting insulin is taken just before or after meals, to control spikes in blood sugar. This type is typically used in addition to a longer-acting insulin.
It often works in 15 minutes, peaks between 30 and 90 minutes, and lasts 3 to 5 hours.
You can take it a few minutes before eating or as you sit down to eat, and it starts to work very quickly.
2.Short-acting insulin
Examples: Humulin R, Novolin R
Short-acting insulin covers your insulin needs during meals. It is taken about 30 minutes to an hour before a meal to help control blood sugar levels.
This type of insulin takes effect in about 30 minutes to one hour, and peaks after two to four hours. Its effects tend to last about five to eight hours.
The biggest advantage of short-acting insulin is that you don’t have to take it at each meal. You can take it at breakfast and supper and still have good control because it lasts a little longer.
3.Intermediate-acting insulin
Examples: Humulin N (NPH), Novolin N (NPH)
Intermediate-acting insulin can control blood sugar levels for about 12 hours or longer, so it can be used overnight.
It begins to work within one to four hours, and peaks between four and 12 hours, depending on the brand.
Intermediate-acting insulin offer baseline insulin coverage and can be used with short-acting insulin or rapid-acting insulin.
4.Long-acting insulin
Examples: Lantus (glargine), Levemir (detemir)
Long-acting insulin has an onset of one hour, and lasts for 20 to 26 hours with no peak.
This insulin type tends to cover your insulin needs for a full day. It is often taken at bedtime.
These long-acting insulin provide 24-hour coverage, and have been helpful at achieving good blood sugar control in type 2 diabetes with just one shot.
5.Pre-mixed insulin
Examples: Humulin 70/30, Novolin 70/30, NovoLog 70/30, Humulin 50/50, Humalog mix 75/25, Humalog mix 50/50
This type of insulin combines intermediate- and short-acting insulin. It is often taken twice a day before meals. It should be taken 10 minutes to 30 minutes before eating.
Pre-mixed insulin takes effect in 5 to 60 minutes, and its peak times vary. Its effects last from 10 to 16 hours.
Pre-mixed insulin was designed to be more convenient. But not everybody has the same insulin requirements, so they don’t fit neatly into the pre-mixed categories.
Type of Insulin
Rapid-acting |
Brand Name
_ NovoLog |
Generic Name
__Insulin aspart |
Onset
15 minutes |
Peak
30 to 90 minutes |
Duration
3 to 5 hours |
---|---|---|---|---|---|
__ Apidra | __ Insulin glulisine | 15 minutes | 30 to 90 minutes | 3 to 5 hours | |
__ Humalog | __ Insulin lispro | 15 minutes | 30 to 90 minutes | 3 to 5 hours |
Type of Insulin
Short-acting |
Brand Name
__ Humulin R |
Generic Name
__ Regular (R) |
Onset
30 to 60 minutes |
Peak
2 to 4 hours |
Duration
5 to 8 hours |
---|---|---|---|---|---|
__ Novolin R |
Type of Insulin
Intermediate-acting |
Brand Name
__ Humulin N |
Generic Name
__ NPH (N) |
Onset
1 to 3 hours |
Peak
8 hours |
Duration
12 to 16 hours |
---|---|---|---|---|---|
__ Novolin N |
Type of Insulin
Long-acting |
Brand Name
__ Levemir |
Generic Name
__ Insulin detemir |
Onset
1 hour |
Peak
Peakless |
Duration
20 to 26 hours |
---|---|---|---|---|---|
__ Lantus | __ Insulin glargine |
Type of Insulin
Pre-mixed NPH |
Brand Name
__ Humulin 70/30 |
Generic Name
__ 70% NPH and 30% regular |
Onset
30 to 60 minutes |
Peak
Varies |
Duration
10 to 16 hours |
---|---|---|---|---|---|
__ Humulin 50/50 | __ 50% NPH and 50% regular | 30 to 60 minutes | Varies | 10 to 16 hours |
Type of Insulin
Pre-mixed insulin lispro protamine suspension (intermediate-acting) and insulin lispro (rapid-acting |
Brand Name
__ Humalog Mix 75/25 |
Generic Name
__ 75% insulin lispro protamine and 25% insulin lispro |
Onset
10 to 15 minutes |
Peak
Varies |
Duration
10 to 16 hours |
---|---|---|---|---|---|
__ Humalog Mix 50/50 | __ 50% insulin lispro protamine and 50% insulin lispro | 10 to 15 minutes | Varies | 10 to 16 hours |
Type of Insulin
Pre-mixed insulin aspart protamine suspension (intermediate-acting) and insulin aspart (rapid-acting) |
Brand Name
__ NovoLog Mix 70/30 |
Generic Name
__ 70% insulin aspart protamine |
Onset
5 to 15 minutes |
Peak
Varies |
Duration
10 to 16 hours |
---|
Insulin cannot be taken as a pill because it would be broken down during digestion just like the protein in food. It must be injected into the fat under your skin for it to get into your blood.
In some rare cases insulin can lead to an allergic reaction at the injection site. Talk to your doctor if you believe you may be experiencing a reaction.
If you have any information,questions, or feedback you would like to include in this webpage.
Please email momo19@diabetessupportsite.com or leave your comments below.